Figure 6: Effect of magnetic targeting on cavitation behaviour in vivo. (a-d) B-mode images with passive acoustic mapping (PAM) overlay for the pulse with highest power for (a) magnetic microbubbles (MMB), (b) MMB + magnet (c) SonoVue and (d) depleted (24 hour old) MMB. (e) Maximum source power for 6 injections per condition for the depleted (24 hour old) MMB sample, MMB, MMB + magnet and SonoVue. Mean value is shown over 6 repeats per condition, error bars represent standard deviation. Asterisks represent statistical significance assessed using 1-way ANOVA followed by Tukey multiple comparisons test (n.s. not significant, **p < 0.01; comparisons not shown have p < 0.001).